On Wednesday 3 Novmber 2021 al 14:00 (CET), Guadalupe Sabio will talk at an EMBO e-talk about the role of stress kinases in cardiometabolic diseases.
To attend the talk yu should register at the following link: https://embo-org.zoom.us/webinar/register/WN_ePJby4iNRbyj0oSxxtgDUQ
The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli. There are four different p38 family members with different roles in relation to cardiac development and function.
The first isoform demonstrated to play an important role in cardiac development was p38α; however, all p38 family members are now known to collaborate in different aspects of cardiomyocyte differentiation and growth. p38 family members have been proposed to have protective and deleterious actions in the stressed myocardium, with the outcome of their action dependent on the model system under study and the identity of the p38 family member activated.
In this talk, we summarize current understanding of the role of the p38 pathway in cardiac physiology and discuss recent advances in the field.